Packers vs. Commanders odds, picks and predictions for Thursday Night Football in Week 2

Sep 12, 2025
Landon McRally
Packers vs. Commanders odds, picks and predictions for Thursday Night Football in Week 2

Why this TNF matchup matters

Washington hasn’t won at Lambeau Field since 1986. That’s the backdrop for a Week 2 Thursday night game between two teams that both looked sharp in their openers—and two fan bases already wondering if this could be a preview of something bigger in January. The betting market picked a side early: Green Bay moved from a 1.5-point favorite at the open to -3.5 by midweek, with a total of 48.5, tied for the highest on the slate.

On paper, it’s strength on strength. Washington, coming off a 12-5 season and a trip to the NFC title game, has embraced a clear identity: run first, stay on schedule, then let quarterback Jayden Daniels stress a defense with designed keepers and option looks. The Commanders churned out 220 rushing yards in Week 1 and have been near automatic when they cross that 150-yard mark—9-0 in games Daniels starts when they do. They also improved to 8-0 in his career when they crack 30 points, a threshold that usually means they’ve dictated pace.

Green Bay answered in their opener with a 27-13 win over Detroit, fueled by a defense that looked quicker, meaner, and far more decisive than it did a year ago. The headline addition is Micah Parsons, and you could see the ripple effects right away. The Lions managed only 50 rushing yards, and the Packers were able to set edges and collapse gaps without selling out the back end. That matters against Daniels, because Washington’s offense is built to punish over-pursuit.

The moneyline is Packers -172, Commanders +145. The shift from -1.5 to -3.5 suggests the market trusts Green Bay’s defense more than Washington’s ability to control things on a short week, on the road, at a venue that amplifies momentum as well as any in the league. The total sitting at 48.5 signals respect for Washington’s explosive run game—and an acknowledgment that if Green Bay scores first, Daniels will be asked to do more through the air.

This is the kind of game where little things stack up fast. Third-and-short for Washington is a green light; third-and-8 is a problem. For Green Bay, a couple of early stops on the quarterback run can tilt the whole script. Add in Thursday-night quirks—short prep, condensed game plans—and the margins get even thinner.

Odds, picks and how the game could play out

Odds, picks and how the game could play out

The spread moved, but the matchup is still simple. Washington wants to make this a 60-minute wrestling match in the trenches; Green Bay wants to make Washington late and predictable on passing downs. If the Commanders are in second-and-5 all night, they’ll carry the ball 35-plus times, bleed the clock, and lean on their red-zone ground concepts. If they’re in second-and-10, Parsons and company can play downhill and force Daniels to hold the ball longer than he wants.

When Washington has the ball, watch the first quarter. Coordinator tendencies tend to stay conservative on Thursday nights, and Washington’s opening script usually leans on zone read, inside zone with a change-of-pace back, and a handful of play-action shots that look like run until the last moment. Daniels’ eyes are on the second-level defenders. If Green Bay’s linebackers step forward too quickly, Washington will pop quick crossers. If they sit, Daniels keeps and tests the edges. The Packers’ answer is discipline: force the give on read plays, rally to the ball, and redirect runs back inside where help is waiting.

Green Bay’s revamped front sets that plan up. Parsons changes geometry; you don’t have to blitz to generate pressure, and that frees up resources to handle option rules. If the Packers can keep Daniels inside the tackle box, his yards come tougher, Washington’s drive lengths shrink, and the explosive plays turn into six-yard wins instead of 26-yard daggers. Expect Green Bay to sprinkle in a spy on clear run looks and switch to zone behind it to cap scrambles. Washington will counter with quick tempo at times to keep the front from subbing and to simplify the looks.

Receivers and tight ends become X-factors in games like this. Washington doesn’t need 300 passing yards; they need two or three timely conversions that pull a safety out of the fit or catch a corner peeking at the backfield. If those hits come early, the Packers will adjust their shell, and that’s when the Commanders find their creases on the ground. If those throws aren’t there, Washington’s third-down distance gets longer, and the sacks and throwaways start to add up.

Now flip it. Green Bay’s offense wants rhythm. It doesn’t have to be flashy—it just has to keep Washington’s defense honest with a steady run-pass mix and a quick-game plan that friendly-fires the pass rush. The Packers were efficient in Week 1 by staying out of obvious passing downs and leaning on motions and play-action to get easy yards. Washington’s defense is physical and fast—if you let them attack vertically down after down, you play right into their hands. Expect the Packers to move the launch point, use jet motion, and spread the ball around to keep the Commanders from teeing off.

Drive finishers decide this one. Washington is built to grind into the red zone; the Packers are built to force field goals. Green Bay’s Week 1 defense tightened near the goal line because it didn’t need extra help on the edges. If that repeats, and Washington ends two long drives with three points instead of seven, the math leans Green Bay. On the other side, Green Bay’s red-zone play calling should emphasize misdirection and condensed formations to avoid negative plays against Washington’s front.

Trends and context help frame the risk:

  • Washington went 9-0 in Daniels starts when rushing for 150+ yards. If they hit that number, they’re hard to beat.
  • Green Bay held Detroit to 50 rushing yards in Week 1 and looked comfortable in early-down run fits.
  • The total is 48.5, tied for the Week 2 high. Thursday games often start slow, especially for road offenses, but one busted run or broken coverage can flip the script.
  • All-time series: Packers lead 22-17-1; Washington last won at Lambeau in 1986. The Commanders did win the most recent meeting (2023), but that was in D.C.

Line movement notes: the jump from -1.5 to -3.5 usually signals either sharp support for the home side, injury cluster concern for the visitor, or both. There’s no obvious single-name injury driving this (as of game day), so the read is market confidence in Green Bay’s defense and home field. The total holding at 48.5 suggests balanced opinions about pace—bettors see paths to shootout and slugfest.

Situational angles matter on a short week:

  • Travel: Washington flies into a tough place to play with a condensed prep window. That usually limits the playbook and the exotic wrinkles.
  • Weather: Early September in Green Bay is usually mild. If wind kicks up or rain rolls in, it tilts slightly toward Washington’s ground game.
  • Coaching: Expect tighter rotations and fewer gadget plays. Thursday plans are about execution, not surprises.

Key chess matchups:

  • QB run rules: Can Green Bay force the give and keep Daniels from turning the corner? If yes, Washington has to win with more traditional inside runs.
  • Edge control vs motion: Washington uses motion to create confusion. How the Packers pass off gaps post-snap will show early if they’re ready.
  • Explosive plays: Washington’s ground game creates light-box shots; Green Bay’s play-action generates crossers behind linebackers. Whoever hits two explosives first likely controls pace.

Best betting angles:

  • Side: Lean Packers -3.5. The market move makes sense with home field, Thursday dynamics, and a defense built to handle QB run. If -3 appears, that’s obviously more attractive.
  • Total: Slight lean to the under 48.5. Washington wants fewer possessions, and Green Bay’s plan is to force long drives. One big-play burst could wreck this, but the script favors a tighter game.
  • Moneyline: Packers -172 for parlay legs or for those who prefer avoiding the hook. The win path is cleaner for Green Bay if they land the first punch.
  • Correlated props: Daniels rushing attempts over (if priced fairly) makes sense if Washington keeps this within one score. Parsons sacks or Green Bay team sacks are live if the Packers build a lead and force longer drops.

How the game could flow: The Packers score first, which nudges Washington to open up on second down more than they’d like. That’s where Daniels has to deliver two or three high-leverage throws on outbreaking routes and crossers. If he hits them, the Commanders can still stack runs and stretch the game. If he doesn’t, Green Bay’s front pins its ears back, and the down-and-distance snowball starts rolling.

Washington will look to counter with tempo and the same two-back looks that worked in Week 1, including the power-read that freed Jacory “Bill” Croskey-Merritt for chunk gains. The Packers’ job is to set edges with a rotating cast and tackle cleanly on first contact. If Croskey-Merritt and Daniels see second-level misses early, Washington will stay stubborn with the run and keep the ball out of harm’s way. If not, they’ll need someone on the perimeter to win quickly and force the Packers out of their comfort shell.

Field position might be the hidden statistic. Washington’s offense is less comfortable driving 75 yards at a time if the quick-hitters aren’t there. Green Bay, meanwhile, can live with a few stalled drives if their defense keeps Washington in the mid-20s for carries rather than the mid-30s. Watch the punt game and hidden yards on returns.

One more number worth flagging: Washington at 30+ points is 8-0 under Daniels. Green Bay knows that threshold, which is why they’ll manage the game even with a lead—eat clock, pick their spots, and avoid short fields off mistakes. If this turns into a possession battle with both teams finishing drives with kicks, that’s a Packers script.

Broadcast note: It’s a Thursday Night Football exclusive on Prime Video, with additional streaming options available through NFL+ and some regional platforms. Kickoff is 8:15 p.m. ET at Lambeau Field, and the setting fits the stakes: two 1-0 teams, early momentum, and the kind of crowd that turns third downs into full-body experiences.

Prediction: Packers vs Commanders leans Green Bay 24, Washington 20. That covers the -3.5 and stays under 48.5, with the Packers’ defense doing just enough to keep Daniels from controlling the night on the ground.